KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH2
All Species:
5.45
Human Site:
S1290
Identified Species:
12
UniProt:
O75038
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75038
NP_055453.2
1416
154668
S1290
P
G
G
T
R
R
V
S
G
P
G
V
R
R
D
Chimpanzee
Pan troglodytes
XP_001149239
1685
188441
L1396
V
E
H
F
Q
R
G
L
R
N
G
Y
C
K
E
Rhesus Macaque
Macaca mulatta
XP_001085424
1423
155915
S1297
P
G
G
T
R
R
V
S
G
P
G
V
R
R
D
Dog
Lupus familis
XP_546733
1387
151432
R1274
R
A
G
R
G
A
R
R
D
A
L
T
E
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
A2AP18
1501
164279
L1375
L
G
V
A
H
Q
V
L
E
P
G
I
R
R
D
Rat
Rattus norvegicus
Q62688
1096
122754
V989
L
I
E
M
A
D
T
V
Q
E
K
I
V
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
K530
L
P
P
S
N
L
S
K
S
N
K
A
D
P
L
Frog
Xenopus laevis
Q32NH8
758
87399
R651
S
I
V
D
P
L
V
R
V
E
I
F
G
V
P
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
S677
W
V
E
I
H
G
V
S
I
D
K
A
R
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
V1211
E
R
G
V
A
E
R
V
R
L
K
Q
T
F
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
R1947
P
K
L
N
R
L
I
R
G
S
W
N
R
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
94
78.7
N.A.
77.2
21.2
N.A.
N.A.
21.2
24.7
24.5
N.A.
24.2
N.A.
N.A.
26.4
Protein Similarity:
100
59.9
95.4
82.9
N.A.
81.6
36.7
N.A.
N.A.
30.7
35.3
35
N.A.
40.3
N.A.
N.A.
35.7
P-Site Identity:
100
13.3
100
6.6
N.A.
46.6
0
N.A.
N.A.
0
6.6
20
N.A.
13.3
N.A.
N.A.
26.6
P-Site Similarity:
100
33.3
100
13.3
N.A.
60
13.3
N.A.
N.A.
6.6
6.6
20
N.A.
13.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
19
10
0
0
0
10
0
19
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% C
% Asp:
0
0
0
10
0
10
0
0
10
10
0
0
10
0
37
% D
% Glu:
10
10
19
0
0
10
0
0
10
19
0
0
10
0
10
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
10
0
10
0
% F
% Gly:
0
28
37
0
10
10
10
0
28
0
37
0
10
0
10
% G
% His:
0
0
10
0
19
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
19
0
10
0
0
10
0
10
0
10
19
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
10
0
0
37
0
0
10
10
% K
% Leu:
28
0
10
0
0
28
0
19
0
10
10
0
0
0
19
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
0
0
0
0
19
0
10
0
10
0
% N
% Pro:
28
10
10
0
10
0
0
0
0
28
0
0
0
10
10
% P
% Gln:
0
0
0
0
10
10
0
0
10
0
0
10
0
19
0
% Q
% Arg:
10
10
0
10
28
28
19
28
19
0
0
0
46
28
0
% R
% Ser:
10
0
0
10
0
0
10
28
10
10
0
0
0
0
0
% S
% Thr:
0
0
0
19
0
0
10
0
0
0
0
10
10
0
0
% T
% Val:
10
10
19
10
0
0
46
19
10
0
0
19
10
10
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _